BSF HCM Previous Year Paper

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BSF HCM Previous Year Paper. We covered all the BSF HCM Previous Year Question Paper PDF download in Hindi in this post for free so that you can practice well for the exam.

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BSF HCM Previous Year Objective Paper for Students

Which of the following is a COX-2 inhibitor?

a) Aspirin

b) Ibuprofen

c) Diclofenac sodium

d) Celecoxib

Option d - Celecoxib

Which of the following adrenergic agonist does not contain a 3, or 4-dihydroxy nucleus?

a) Ephedrine

b) Albuterol

c) Phenylpropanolamine

d) Terbutaline

Option b - Albuterol

…….. is a selective ACE inhibitor.

a) Atenolol

b) Ramipril

c) Losartan

d) Nifedipine

Option b - Ramipril

Which of the following is third-generation fluoro quinolone?

a) Lomefloxacin

b) Ciprofloxacin

c) Gemifloxacin

d) Gatifoxacin

Option d - Gatifoxacin

QSAR stands for.

a) Qualitative structure-activity relationship

b) Quantitative structure action relationship

c) Quantitative structure-activity relationship

d) Qualitative structure activity relativity

Option c - Quantitative structure-activity relationship

Which of the following is a cholesterol absorption inhibitor?

a) Atorvastatin

b) Ezetimible

c) Fenofibrate

d) Nicotinic acid

Option b - Ezetimible

One of the following is HIV NHRT inhibitors.

a) Lopinavir

b) Efavirenz

c) Zidovudine

d) Acyclovir

Option b - Efavirenz

Which of the following is not a sulpha drug?

a) Captopril

b) Enalapril

c) Fosinopril

d) Losartan

Option a - Captopril

Most of the drugs are absorbed in the body by means of.

a) Active transport

b) Passive transport

c) Ion-pair transport

d) Facilitated diffusion

Option b - Passive transport

Insulin stimulates glucose transport by promoting the translocation of.

a) GLUT4

b) GLUT 2 and GLUT 4

c) GLUT 1 and GLUT 4

d) GLUT2

Option c - GLUT 1 and GLUT 4

Ptyline is secreted by.

a) Pancreas

b) Lachrymal gland

c) Parotid gland

d) None of the above

Option c - Parotid gland

The most useful class of drugs in the long-term treatment of hypertension is.

a) Thiazide diuretics

b) Osmotic diuretics

c) Mercurial diuretics

d) Pentazocine

Option a - Thiazide diuretics

Which of the following drug is not acting on the opioid (Kappa) receptor?

a) Buprenorphine

b) Butorphanol

c) Nalbuphine

d) Pentazocine

Option a - Buprenorphine

Which of the following crosses the blood-brain barrier?

a) GABA

b) Propranolol

c) Suxamethonium

d) Dopamine

Option b - Propranolol

Select the synonyms of aconite root.

a) Vachang

b) Mouckshood

c) All of the above

d) None of above

Option c - All of the above

Diosgenin is ……

a) An alkaloid obtained from Dioscorea

b) A carbohydrate from Dioscorea

c) A glycoside from Dioscorea

d) None of above

Option c - A glycoside from Dioscorea

Glandula hair having a unicellular or occasionally a short unicellular padiel with a unicellular or bicellular terminal gland is characteristic of.

a) Senna leaves

b) Belladonna Leaves

c) Datura Stramonium leaves

d) Digitalis purpurea leaves

Option d - Digitalis purpurea leaves

The drug is bacterial to all three pools of extracellular, intracellular, and necrotic caseum of tubercle bacilli.

a) Isoniazide

b) Ethambutol

c) Pyrazinamide

d) Rifampin

Option d - Rifampin

Many drugs are chiral. In a synthesis of chiral drug molecules in a symmetric environment.

a) Always one enantiomer is obtained

b) Always both enantiomers are in equal amounts

c) Always both enantiomers are in equal amounts

d) None of the above

Option b - Always both enantiomers are in equal amounts

In mammals, the major fat in adipose tissue is.

a) Triglyceride

b) Cholesterol

c) Sphingolipids

d) Phospholipids

Option a - Triglyceride

Ferritin is.

a) Coenzyme

b) The stored form of iron

c) Non-protein moiety

d) Isoenzyme

Option b - The stored form of iron

The active form of Vitamin D in man is.

a) Cholecalciferol

b) Calcifediol

c) Calciferol

d) Calcitriol

Option d - Calcitriol

Isotopes differ in.

a) The number of protons

b) The valency number

c) The chemical activity

d) The number of neutrons

Option d - The number of neutrons

The purity of water for injection is checked by.

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a) Potential testing

b) Pyrogen testing

c) Conductivity testing

d) pH Testing

Option c - Conductivity testing

Geometrical isomerism is possible in a case.

a) 2-Pentene

b) Pentane

c) Propene

d) Ethene

Option a - 2-Pentene

Sanguiamarine belongs to the subgroup of.

a) Morphinans

b) Benzyl isoquinolines

c) Phtalide isoquinolines

d) Benzophenathrenes

Option b - Benzyl isoquinolines

Dovers powder is used as a diaphoretic contains.

a) Ipecac and Opium

b) Senna and Cinchona

c) Opium and cinchona

d) All of the above

Option a - Ipecac and Opium

.......... is the dimmer fo flavones and flavonones.

a) Chalcones

b) Aurones

c) Biflavanoids

d) Dihydroflavones

Option c - Biflavanoids

The wavelength source in the NMR spectrometer is.

a) Goniometer

b) Radiofrequency oscillator

c) High voltage generator

d) Klystron oscillator

Option b - Radiofrequency oscillator

Morphine does not cause.

a) Constriction of the pupil.

b) CNS depression

c) Respiratory depression

d) Diarrhoea

Option d - Diarrhoea

O, M, and P-isomers can be differentiated on the basis of.

a) Chemical Shift

b) Coupling constant

c) Extinction coefficient

d) Dipole moment

Option b - Coupling constant

The plasma drug concentration in mcg/ml data obtained after the oral administration of 50mg of a drug are 5.5 in 1h, 9.2 in 2h, 14.9in 3h, 10.3 in 4h, 7.1 in 5 h and 2.2 in 6h. the AUC for the blood data will be.

a) 45.35 mcg/ml.h

b) 55.35 mcg/ml.h

c) 50.35 mcg/ml.h

d) 46.35 mcg/ml.h

Option a - 45.35 mcg/ml.h

Schleuniger tester is used for the tablets to measure

a) Roughness

b) Hardness

c) Dissolution

d) Friability

Option b - Hardness

Creatinine clearance is used as a measurement.

a) Passive renal absorption

b) Glomerular filtration rate

c) Drug metabolism rate

d) Renal excretion rate

Option b - Glomerular filtration rate

Capping in tablets mainly occurs due to.

a) Less upper punch pressure

b) Poor flowability of granules

c) Proper formulation design

d) Entrapment of air in tablet during compression

Option d - Entrapment of air in tablet during compression

The Franz diffusion cell which is used for the evaluation of transdermal drug delivery systems consists of.

a) 1 chamber

b) 2 chambers

c) 3 chambers

d) None of above

Option b - 2 chambers

Quick-breaking aerosols are applicable.

a) Orally

b) Parenterally

c) Topical

d) Ophthalmically

Option c - Topical

In an osmotic drug delivery system, the drug is released.

a) Polymeric matrix

b) Delivery orifice

c) Plastic matrix

d) None of the these

Option b - Delivery orifice

The parenteral product must be.

a) Packed-in bottle

b) Sterilized

c) Free from viable

d) living organism

Option b - Sterilized

A water attack test is generally performed.

a) USP type I glass

b) USP type II glass

c) USP type III glass

d) All of above

Option b - USP type II glass

Silicone-based adhesives used in transdermal drug delivery possess.

a) Excellent chemical stability

b) Low toxicity

c) Skin compatibility

d) All of the above

Option d - All of the above

Dose dumping may be a general problem in the formulation of.

a) Soft gelatin capsules

b) Suppositories

c) Modified-release drug products

d) None of the above

Option c - Modified-release drug products

Which of the following is useful as a diluent, binder, disintegrating agent as well as a lubricant in tablet formulations?

a) Starch

b) Tragacanth

c) Sucrose

d) None of above

Option a - Starch

Homatropine is a.

a) Tropine ester of amino acetic acid

b) Tropine ester of mandelic acid

c) Tropine methyl bromide ester of mandelic acid

d) Tropine ester of amino formic acid

Option b - Tropine ester of mandelic acid

A list of the drugs whose import, manufacture and sale, labeling, and packaging are governed by special provisions are included in the schedule.

a) X

b) K

c) H

d) G

Option b - K

Which of the following radiation has the greatest penetrating powder?

a) Alpha radiation

b) Beta radiation

c) Gamma radiation

d) UV radiation

Option c - Gamma radiation

The energy produced in the UV region produces changes in the.

a) The rotation energy of the molecule

b) The vibrational energy of the molecule

c) The electronic energy of the molecule

d) All of the above

Option c - The electronic energy of the molecule

Sanguiamarine belongs to the subgroup of.

a) Morphinans

b) Benzyl isoquinolines

c) Phthalide isoquinolines

d) Benzophenatherenes

Option b - Benzyl isoquinolines

Dovers powder is used as a diaphoretic contains.

a) Ipecac and Opium

b) Senna and Cinchona

c) Opium and Cinchona

d) All of above

Option a - pecac and Opium

……….. is the dimmer of flavones and flavonones.

a) Chalcones

b) Aurones

c) Biflavanoids

d) Dihydrofalvones

Option b - Aurones

Isoquinoline alkaloids are biosynthesized via …… pathway.

a) Shikimic acid-tyrosine

b) Shikimic acid-tryptophan

c) Shikimic acid-cathinone

d) None of above

Option a - Shikimic acid-tyrosine

…………. is a precursor for indole alkaloids.

a) Strictosidine

b) Diosgenin

c) Ornithine

d) Hygrine

Option a - Strictosidine

Catharanthine is an alkaloid of ……. type.

a) Coryname

b) Ibogane

c) Aspidospermane

d) All of above

Option b - Ibogane

Different kinds of currents contribute to the polarographic wave.

a) Residual current

b) Migration Current

c) Diffusion current

d) All of the above

Option d - All of the above

The most common causative agent of bacterial pneumonia.

a) Staphylococcus aureus

b) Escherichia coli

c) Sterptococcus pneumonia

d) Mycopalsma pneumonia

Option c - Sterptococcus pneumonia

Which one of the following devices is useful to increase the efficiency of drug delivery via aerosols?

a) Tube spacer

b) Metered value

c) Actuator

d) Pressure value

Option b - Metered value

Dienosterol is synthesized starting from.

a) p-Hydroxyl acetophenone

b) p-Chloro-propiophenone

c) p-Hydroxy propiophenone

d) p-Chloro acetophenone

Option c - p-Hydroxy propiophenone

Ethacrynic acid belongs to the class of.

a) Loop Diuretic

b) ACE inhibitor

c) Aldosterone antagonist

d) Thiazide derivative

Option a - Loop Diuretic

In cephalosporins, the lactam ring is fused with.

a) Thiazolidine system

b) 1,3 dihyrothiazine system

c) Thiazine system

d) Dehydro thiazolidine system

Option a - Thiazolidine system

Which of the following is a ß-Lactamse inhibitor?

a) Chloram phenicol

b) Cefadroxil

c) Clavunilic acid

d) Ampicillin

Option c - Clavunilic acid

Penicilline on hydrolysis with alkali gives.

a) Penicilloic acid

b) Penaldic acid

c) Penicillic acid

d) Penicillamine

Option a - Penicilloic acid

The therapeutic effect of theophylline is achieved at plasma conc. of.

a) 05-15 µg/mL

b) 10-20 µg/mL

c) 15-25 µg/mL

d) 20-30 µg/mL

Option b - 10-20 µg/mL

One of the following antihypertensives has a similar structure as that of the diuretic agent chlorothiazide.

a) Minoxidil

b) Diazoxide

c) Guanethidine

d) Propranolol

Option b - Diazoxide

Condensation of N-m-hydroxy phenyl 1-N-p-tolyl glycine with ethylene diamine gives.

a) Tolazoline

b) Phentolamine

c) Prazocin

d) Phenoxybenzamine

Option b - Phentolamine

An important example of liquid-liquid partition chromatography is.

a) Thin layer

b) Column

c) Paper

d) Ion exchange

Option c - Paper

In amperometric titrationsm, one of the following is kept constant.

a) Current

b) Resistance

c) Voltage applied

d) Conductance

Option c - Voltage applied

In any colorimeter.

a) Unabsorbed radiation is measured

b) Absorbed radiation is measured

c) Absorbed radiation intensity is measured

d) None of above

Option c - Absorbed radiation intensity is measured

Supercritical fluid chromatography is specifically used for the analysis.

a) Thermolabile compounds

b) Thermolabile macromolecules

c) Thermostable macromolecules

d) None of above

Option b - Thermolabile macromolecules

An interferone filter consists of.

a) An iron plate coated with selenium

b) A layer of silver on both sides of MgF, deposited on glass

c) A Tungson plate coated with Ago

d) A solid sheet of glass colored by pigment

Option d - A solid sheet of glass colored by pigment

Tetrabutyl ammonium phosphate is used in HPLC.

a) For adjusting the pH of the mobile phase

b) As stationary phase

c) As a chelating agent

d) As ion pairing agent for anions

Option b - As stationary phase

Desipramine is metabolized in the liver mainly by. ( bsf hcm previous year paper )

a) N-Oxidation

b) Hydroxylation

c) Both A and B

d) Alkylating agent

Option a - N-Oxidation

2-Amono pyridine and 2-dimethyl amino ethyl chloride are starting materials for the synthesis. ( bsf hcm previous year paper )

a) Mepyramine

b) Diphenhydramine

c) Chlorpheniramine

d) Pheniramine

Option a - Mepyramine

A 50-year-old male farm worker is brought to the emergency room. He was found confused in the orchard and since then lost consciousness. His heart rate is 45 and his blood pressure is 80/40mmHg. He is sweating and salivating profusesły. Which of the treatment is indicated?

a) Physostigmine

b) Norepinephrine

c) Trimethaphan

d) Atropine

Option d - Atropine

A 45-year-old man who has been injured in a car accident is brought into the emergency room. His blood alcohol level on admission is 275 mg/dL. Hospital records show a prior hospitalization for alcohol-related seizures. His wife confirms that he has been drinking heavily for 3 weeks. What treatment should be provided to the patient if he goes into withdrawal?

a) Pentobarbital

b) Lorazepam

c) Benzodiazepine

d) Phenytoin

Option d - Phenytoin

The mechanism of action of Ketoconazole is.

a) Inhibits ergosterol synthesis

b) Inhibits DNA gyrase

c) Inhibits dihydropteroate synthetase

d) Induces translation misreadings

Option a - Inhibits ergosterol synthesis

Monitoring plasma drug concentration is useful while using. ( bsf hcm previous year paper )

a) Antihypertensive drugs

b) Levodopa

c) Lithium carbonate

d) MAO inhibitors

Option c - Lithium carbonate

Phase I oxidative processes frequency involves all of the following, except.

a) Cytochrome P-450

b) NADPH and NADP cofactors

c) Liver endoplasmic reticulum

d) Esterases

Option d - Esterases

All of the following drugs are useful in treating complex partial seizures, except.

a) Ethozuximide

b) Phenobarbital

c) Carbamazepine

d) Phenytoin

Option a - Ethozuximide

Patients suffering from multidrug-resistant tuberculosis can be treated with all of the following drugs.

a) Tobramycin

b) Amikacin

c) Ciprofloxacin

d) Clarithromycin

Option d - Clarithromycin

Which of the following anti-malarial drug is safe during pregnancy?

a) Amodiaquine.

b) Proguanil

c) Primaquine

d) chloroquine

Option d - chloroquine

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