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BSF HCM Previous Year Objective Paper for Students
Which of the following is a COX-2 inhibitor?
a) Aspirin
b) Ibuprofen
c) Diclofenac sodium
d) Celecoxib
Option d - Celecoxib
Which of the following adrenergic agonist does not contain a 3, or 4-dihydroxy nucleus?
a) Ephedrine
b) Albuterol
c) Phenylpropanolamine
d) Terbutaline
Option b - Albuterol
…….. is a selective ACE inhibitor.
a) Atenolol
b) Ramipril
c) Losartan
d) Nifedipine
Option b - Ramipril
Which of the following is third-generation fluoro quinolone?
a) Lomefloxacin
b) Ciprofloxacin
c) Gemifloxacin
d) Gatifoxacin
Option d - Gatifoxacin
QSAR stands for.
a) Qualitative structure-activity relationship
b) Quantitative structure action relationship
c) Quantitative structure-activity relationship
d) Qualitative structure activity relativity
Option c - Quantitative structure-activity relationship
Which of the following is a cholesterol absorption inhibitor?
a) Atorvastatin
b) Ezetimible
c) Fenofibrate
d) Nicotinic acid
Option b - Ezetimible
One of the following is HIV NHRT inhibitors.
a) Lopinavir
b) Efavirenz
c) Zidovudine
d) Acyclovir
Option b - Efavirenz
Which of the following is not a sulpha drug?
a) Captopril
b) Enalapril
c) Fosinopril
d) Losartan
Option a - Captopril
Most of the drugs are absorbed in the body by means of.
a) Active transport
b) Passive transport
c) Ion-pair transport
d) Facilitated diffusion
Option b - Passive transport
Insulin stimulates glucose transport by promoting the translocation of.
a) GLUT4
b) GLUT 2 and GLUT 4
c) GLUT 1 and GLUT 4
d) GLUT2
Option c - GLUT 1 and GLUT 4
Ptyline is secreted by.
a) Pancreas
b) Lachrymal gland
c) Parotid gland
d) None of the above
Option c - Parotid gland
The most useful class of drugs in the long-term treatment of hypertension is.
a) Thiazide diuretics
b) Osmotic diuretics
c) Mercurial diuretics
d) Pentazocine
Option a - Thiazide diuretics
Which of the following drug is not acting on the opioid (Kappa) receptor?
a) Buprenorphine
b) Butorphanol
c) Nalbuphine
d) Pentazocine
Option a - Buprenorphine
Which of the following crosses the blood-brain barrier?
a) GABA
b) Propranolol
c) Suxamethonium
d) Dopamine
Option b - Propranolol
Select the synonyms of aconite root.
a) Vachang
b) Mouckshood
c) All of the above
d) None of above
Option c - All of the above
Diosgenin is ……
a) An alkaloid obtained from Dioscorea
b) A carbohydrate from Dioscorea
c) A glycoside from Dioscorea
d) None of above
Option c - A glycoside from Dioscorea
Glandula hair having a unicellular or occasionally a short unicellular padiel with a unicellular or bicellular terminal gland is characteristic of.
a) Senna leaves
b) Belladonna Leaves
c) Datura Stramonium leaves
d) Digitalis purpurea leaves
Option d - Digitalis purpurea leaves
The drug is bacterial to all three pools of extracellular, intracellular, and necrotic caseum of tubercle bacilli.
a) Isoniazide
b) Ethambutol
c) Pyrazinamide
d) Rifampin
Option d - Rifampin
Many drugs are chiral. In a synthesis of chiral drug molecules in a symmetric environment.
a) Always one enantiomer is obtained
b) Always both enantiomers are in equal amounts
c) Always both enantiomers are in equal amounts
d) None of the above
Option b - Always both enantiomers are in equal amounts
In mammals, the major fat in adipose tissue is.
a) Triglyceride
b) Cholesterol
c) Sphingolipids
d) Phospholipids
Option a - Triglyceride
Ferritin is.
a) Coenzyme
b) The stored form of iron
c) Non-protein moiety
d) Isoenzyme
Option b - The stored form of iron
The active form of Vitamin D in man is.
a) Cholecalciferol
b) Calcifediol
c) Calciferol
d) Calcitriol
Option d - Calcitriol
Isotopes differ in.
a) The number of protons
b) The valency number
c) The chemical activity
d) The number of neutrons
Option d - The number of neutrons
The purity of water for injection is checked by.
a) Potential testing
b) Pyrogen testing
c) Conductivity testing
d) pH Testing
Option c - Conductivity testing
Geometrical isomerism is possible in a case.
a) 2-Pentene
b) Pentane
c) Propene
d) Ethene
Option a - 2-Pentene
Sanguiamarine belongs to the subgroup of.
a) Morphinans
b) Benzyl isoquinolines
c) Phtalide isoquinolines
d) Benzophenathrenes
Option b - Benzyl isoquinolines
Dovers powder is used as a diaphoretic contains.
a) Ipecac and Opium
b) Senna and Cinchona
c) Opium and cinchona
d) All of the above
Option a - Ipecac and Opium
.......... is the dimmer fo flavones and flavonones.
a) Chalcones
b) Aurones
c) Biflavanoids
d) Dihydroflavones
Option c - Biflavanoids
The wavelength source in the NMR spectrometer is.
a) Goniometer
b) Radiofrequency oscillator
c) High voltage generator
d) Klystron oscillator
Option b - Radiofrequency oscillator
Morphine does not cause.
a) Constriction of the pupil.
b) CNS depression
c) Respiratory depression
d) Diarrhoea
Option d - Diarrhoea
O, M, and P-isomers can be differentiated on the basis of.
a) Chemical Shift
b) Coupling constant
c) Extinction coefficient
d) Dipole moment
Option b - Coupling constant
The plasma drug concentration in mcg/ml data obtained after the oral administration of 50mg of a drug are 5.5 in 1h, 9.2 in 2h, 14.9in 3h, 10.3 in 4h, 7.1 in 5 h and 2.2 in 6h. the AUC for the blood data will be.
a) 45.35 mcg/ml.h
b) 55.35 mcg/ml.h
c) 50.35 mcg/ml.h
d) 46.35 mcg/ml.h
Option a - 45.35 mcg/ml.h
Schleuniger tester is used for the tablets to measure
a) Roughness
b) Hardness
c) Dissolution
d) Friability
Option b - Hardness
Creatinine clearance is used as a measurement.
a) Passive renal absorption
b) Glomerular filtration rate
c) Drug metabolism rate
d) Renal excretion rate
Option b - Glomerular filtration rate
Capping in tablets mainly occurs due to.
a) Less upper punch pressure
b) Poor flowability of granules
c) Proper formulation design
d) Entrapment of air in tablet during compression
Option d - Entrapment of air in tablet during compression
The Franz diffusion cell which is used for the evaluation of transdermal drug delivery systems consists of.
a) 1 chamber
b) 2 chambers
c) 3 chambers
d) None of above
Option b - 2 chambers
Quick-breaking aerosols are applicable.
a) Orally
b) Parenterally
c) Topical
d) Ophthalmically
Option c - Topical
In an osmotic drug delivery system, the drug is released.
a) Polymeric matrix
b) Delivery orifice
c) Plastic matrix
d) None of the these
Option b - Delivery orifice
The parenteral product must be.
a) Packed-in bottle
b) Sterilized
c) Free from viable
d) living organism
Option b - Sterilized
A water attack test is generally performed.
a) USP type I glass
b) USP type II glass
c) USP type III glass
d) All of above
Option b - USP type II glass
Silicone-based adhesives used in transdermal drug delivery possess.
a) Excellent chemical stability
b) Low toxicity
c) Skin compatibility
d) All of the above
Option d - All of the above
Dose dumping may be a general problem in the formulation of.
a) Soft gelatin capsules
b) Suppositories
c) Modified-release drug products
d) None of the above
Option c - Modified-release drug products
Which of the following is useful as a diluent, binder, disintegrating agent as well as a lubricant in tablet formulations?
a) Starch
b) Tragacanth
c) Sucrose
d) None of above
Option a - Starch
Homatropine is a.
a) Tropine ester of amino acetic acid
b) Tropine ester of mandelic acid
c) Tropine methyl bromide ester of mandelic acid
d) Tropine ester of amino formic acid
Option b - Tropine ester of mandelic acid
A list of the drugs whose import, manufacture and sale, labeling, and packaging are governed by special provisions are included in the schedule.
a) X
b) K
c) H
d) G
Option b - K
Which of the following radiation has the greatest penetrating powder?
a) Alpha radiation
b) Beta radiation
c) Gamma radiation
d) UV radiation
Option c - Gamma radiation
The energy produced in the UV region produces changes in the.
a) The rotation energy of the molecule
b) The vibrational energy of the molecule
c) The electronic energy of the molecule
d) All of the above
Sanguiamarine belongs to the subgroup of.
a) Morphinans
b) Benzyl isoquinolines
c) Phthalide isoquinolines
d) Benzophenatherenes
Option b - Benzyl isoquinolines
Dovers powder is used as a diaphoretic contains.
a) Ipecac and Opium
b) Senna and Cinchona
c) Opium and Cinchona
d) All of above
Option a - pecac and Opium
……….. is the dimmer of flavones and flavonones.
a) Chalcones
b) Aurones
c) Biflavanoids
d) Dihydrofalvones
Option b - Aurones
Isoquinoline alkaloids are biosynthesized via …… pathway.
a) Shikimic acid-tyrosine
b) Shikimic acid-tryptophan
c) Shikimic acid-cathinone
d) None of above
Option a - Shikimic acid-tyrosine
…………. is a precursor for indole alkaloids.
a) Strictosidine
b) Diosgenin
c) Ornithine
d) Hygrine
Option a - Strictosidine
Catharanthine is an alkaloid of ……. type.
a) Coryname
b) Ibogane
c) Aspidospermane
d) All of above
Option b - Ibogane
Different kinds of currents contribute to the polarographic wave.
a) Residual current
b) Migration Current
c) Diffusion current
d) All of the above
Option d - All of the above
The most common causative agent of bacterial pneumonia.
a) Staphylococcus aureus
b) Escherichia coli
c) Sterptococcus pneumonia
d) Mycopalsma pneumonia
Option c - Sterptococcus pneumonia
Which one of the following devices is useful to increase the efficiency of drug delivery via aerosols?
a) Tube spacer
b) Metered value
c) Actuator
d) Pressure value
Option b - Metered value
Dienosterol is synthesized starting from.
a) p-Hydroxyl acetophenone
b) p-Chloro-propiophenone
c) p-Hydroxy propiophenone
d) p-Chloro acetophenone
Option c - p-Hydroxy propiophenone
Ethacrynic acid belongs to the class of.
a) Loop Diuretic
b) ACE inhibitor
c) Aldosterone antagonist
d) Thiazide derivative
Option a - Loop Diuretic
In cephalosporins, the lactam ring is fused with.
a) Thiazolidine system
b) 1,3 dihyrothiazine system
c) Thiazine system
d) Dehydro thiazolidine system
Option a - Thiazolidine system
Which of the following is a ß-Lactamse inhibitor?
a) Chloram phenicol
b) Cefadroxil
c) Clavunilic acid
d) Ampicillin
Option c - Clavunilic acid
Penicilline on hydrolysis with alkali gives.
a) Penicilloic acid
b) Penaldic acid
c) Penicillic acid
d) Penicillamine
Option a - Penicilloic acid
The therapeutic effect of theophylline is achieved at plasma conc. of.
a) 05-15 µg/mL
b) 10-20 µg/mL
c) 15-25 µg/mL
d) 20-30 µg/mL
Option b - 10-20 µg/mL
One of the following antihypertensives has a similar structure as that of the diuretic agent chlorothiazide.
a) Minoxidil
b) Diazoxide
c) Guanethidine
d) Propranolol
Option b - Diazoxide
Condensation of N-m-hydroxy phenyl 1-N-p-tolyl glycine with ethylene diamine gives.
a) Tolazoline
b) Phentolamine
c) Prazocin
d) Phenoxybenzamine
Option b - Phentolamine
An important example of liquid-liquid partition chromatography is.
a) Thin layer
b) Column
c) Paper
d) Ion exchange
Option c - Paper
In amperometric titrationsm, one of the following is kept constant.
a) Current
b) Resistance
c) Voltage applied
d) Conductance
Option c - Voltage applied
In any colorimeter.
a) Unabsorbed radiation is measured
b) Absorbed radiation is measured
c) Absorbed radiation intensity is measured
d) None of above
Option c - Absorbed radiation intensity is measured
Supercritical fluid chromatography is specifically used for the analysis.
a) Thermolabile compounds
b) Thermolabile macromolecules
c) Thermostable macromolecules
d) None of above
Option b - Thermolabile macromolecules
An interferone filter consists of.
a) An iron plate coated with selenium
b) A layer of silver on both sides of MgF, deposited on glass
c) A Tungson plate coated with Ago
d) A solid sheet of glass colored by pigment
Option d - A solid sheet of glass colored by pigment
Tetrabutyl ammonium phosphate is used in HPLC.
a) For adjusting the pH of the mobile phase
b) As stationary phase
c) As a chelating agent
d) As ion pairing agent for anions
Option b - As stationary phase
Desipramine is metabolized in the liver mainly by. ( bsf hcm previous year paper )
a) N-Oxidation
b) Hydroxylation
c) Both A and B
d) Alkylating agent
Option a - N-Oxidation
2-Amono pyridine and 2-dimethyl amino ethyl chloride are starting materials for the synthesis. ( bsf hcm previous year paper )
a) Mepyramine
b) Diphenhydramine
c) Chlorpheniramine
d) Pheniramine
Option a - Mepyramine
A 50-year-old male farm worker is brought to the emergency room. He was found confused in the orchard and since then lost consciousness. His heart rate is 45 and his blood pressure is 80/40mmHg. He is sweating and salivating profusesły. Which of the treatment is indicated?
a) Physostigmine
b) Norepinephrine
c) Trimethaphan
d) Atropine
Option d - Atropine
a) Pentobarbital
b) Lorazepam
c) Benzodiazepine
d) Phenytoin
Option d - Phenytoin
The mechanism of action of Ketoconazole is.
a) Inhibits ergosterol synthesis
b) Inhibits DNA gyrase
c) Inhibits dihydropteroate synthetase
d) Induces translation misreadings
Option a - Inhibits ergosterol synthesis
Monitoring plasma drug concentration is useful while using. ( bsf hcm previous year paper )
a) Antihypertensive drugs
b) Levodopa
c) Lithium carbonate
d) MAO inhibitors
Option c - Lithium carbonate
Phase I oxidative processes frequency involves all of the following, except.
a) Cytochrome P-450
b) NADPH and NADP cofactors
c) Liver endoplasmic reticulum
d) Esterases
Option d - Esterases
All of the following drugs are useful in treating complex partial seizures, except.
a) Ethozuximide
b) Phenobarbital
c) Carbamazepine
d) Phenytoin
Option a - Ethozuximide
Patients suffering from multidrug-resistant tuberculosis can be treated with all of the following drugs.
a) Tobramycin
b) Amikacin
c) Ciprofloxacin
d) Clarithromycin
Option d - Clarithromycin
Which of the following anti-malarial drug is safe during pregnancy?
a) Amodiaquine.
b) Proguanil
c) Primaquine
d) chloroquine
Option d - chloroquine
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