DSSSB Head Clerk Previous Year Paper

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DSSSB Head Clerk Previous Year Objective Paper for Students

In the Liberman-Burchard test for steroids, the compound is dissolved in.

a) Methanol

b) Chloroform

c) Benzene

d) Ethanol

Option b – Chloroform

Rutin is extracted from all of the following, except ( DSSSB Head Clerk Previous Year MCQ )

a) Sophora Japonica

b) Fagopyrum esculentum

c) Eucalyptus macrorrhyncha

d) Ginko biloba

Option d – Ginko biloba

cinchona robusta is a hybrid of.

a) C.Calisaya and C micrantha

b) C. Succirubra and C. Officinalis

c) C. Calisaya and C. Officinalis

d) C. Calisaya and C. Succirubra

Option b – C. Succirubra and C. Officinalis

The microscopical character of the flower buds of Eugenia Caryophullus is ( DSSSB Head Clerk Previous Year MCQ )

a) Collenchymatous parenchyma containing in its outer part numberous. ellipsoidal schizolysigenous oil glands

b) Small translucent endosperm containing aleurone grains

c) Wide parenchymatous starchy cortex, the endosperm containing volatile oils

d) Outer surface consisting of external perisperm, rough, dark brown with reticulate furrows

Option a – Collenchymatous parenchyma containing in its outer part numberous. ellipsoidal schizolysigenous oil glands

The Schedule in D and C Act that deals with the standard for disinfection fluids is.

a) Schedule – O

b) Schedule – F

c) Schedule – B

d) Schedule – M

Option a – Schedule – O

Single cells in tissue culture can be isolated by all of the following ( DSSSB Head Clerk Previous Year MCQ )

a) Mechanical method

b) Filter paper method

c) Enzymatic method

d) Suspension culture.

Option b – Filter paper method

The purpose of seal coating in the sugar coating process for tablets is.

a) To prevent moisture penetration into the tablet core

b) To round the edges and build up the tablet weight

c) To impart the desired color to the table

d) To give lusture to the tablet

Option a – To prevent moisture penetration into the tablet core

Lactose is the most widely used diluent in tablet formulation. However, it is not used in the formulation of which one of the following? ( DSSSB Head Clerk Previous Year MCQ )

a) Pyrazinamide

b) Ibuprofen

c) Sulfacetamide

d) Isoniazide

Option d – Isoniazide

One thousand nanograms equal one.

a) Centigram

b) Gram

c) Kilogram

d) Microgram

Option d – Microgram

Aglcone of the steroidal saponins is commonly referred to as a “Spirostane” due to its spiro character of ( DSSSB Head Clerk Previous Year MCQ )

a) C 22

b) C 19

c) C13

d) C 18

Option a – C 22

Ephedra sinica and Ephedra equisentia can be distinguished by type.

a) Branching

b) Stomata

c) Scaly leaves

d) Alkaloids

Option c – Scaly leaves

Tetraterpenoids include which of the following ( DSSSB Head Clerk Previous Year MCQ )

a) Carotenes

b) Xanthophylls

c) Caroteoidic acid

d) All of above

Option d – All of above

Vincristine and Vinblastine act by.

a) Interfering with the synthesis of t-RNA

b) Inhibiting the fragmentation of DNA

c) Binding of Protein

d) Incorporating into folic acid metabolism

Option c – Binding of Protein

The lycopodium spore method can be used to find out the percentage purity of crude drugs which contains ( DSSSB Head Clerk Previous Year MCQ )

a) Multi-layered cells or tissues

b) Well-defined particles can be counted

c) Oil globules

d) Characteristics of particles of irregular thickness, the length of which can be measured

Option b – Well-defined particles can be counted

Creatinine clearance is used as a.

a) Glomerular filtration rate

b) Renal excretion rate

c) Drug metabolism rate

d) Passive renal excretion

Option a – Glomerular filtration rate

The most common causative agent of bacterial pneumonia is ( DSSSB Head Clerk Previous Year MCQ )

a) Bacillus stearothermophilis

b) Spores of B. subtilis

c) Streptococcus pneumonia

d) Mycoplasma pneumonia

Option c – Streptococcus pneumonia

The metabolic function of Riboflavin involves the following.

a) FMN and FAD

b) NADP and NADPH

c) AMP and ATP

d) Retin and Retinine

Option a – FMN and FAD

Bacteria that can derive their nutritional requirements and energy from similar inorganic sources are called ( DSSSB Head Clerk Previous Year MCQ )

a) Autotrophic

b) Heterotrophic

c) Parasite

d) Saprophyte

Option a – Autotrophic

Which of the following can be given for the treatment of Scurvy?

a) Vitamin A

b) Vitamin D

c) Vitamin C

d) Vitamin E

Option c – Vitamin C

Yeast is a rich source of ( DSSSB Head Clerk Previous Year MCQ )

a) Vitamin A

b) Vitamin B

c) Vitamin C

d) VitaminD

Option b – Vitamin B

BCG vaccine should be given at.

a) Birth

b) 6 – Month

c) 1 – Year

d) 2-Year

Option a – Birth

Which of the following can be given for good bone health? ( DSSSB Head Clerk Previous Year MCQ )

a) Vitamin – A

b) Vitamin-D

c) Vitamin – C

d) Vitamin – E

Option b – Vitamin-D

Enzymes are referred to as spreading factors.

a) Heparin

b) Chondroitin

c) Hyaluronidase

d) Iduronic acid

Option c – Hyaluronidase

Antigenic preparation is made from extracellular toxins.

a) Vaccines

b) Toxoids

c) Endotoxinst

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d) Sera

Option b – Toxoids

Which vitamin is known as an anti-sterility factor?

a) Vitamin K

b) Vitamin D

c) Vitamin E

d) Vitamin A

Option c – Vitamin E

Which of the following is the richest source of Lecithin?

a) Meat

b) Fish

c) Chicken

d) Egg Yolk

Option d – Egg Yolk

Passive immunity is obtained by injecting.

a) Antiserum

b) Antigens

c) Vaccines

d) Antibodies

Option d – Antibodies

An acid contained in the bacterial cell walls is.

a) Muranic acid

b) Formic acid

c) Stearic acid

d) Palmitic acid

Option a – Muranic acid

A preparation containing killed or attenuated viruses are termed as.

a) Vaccine

b) Antiserum

c) Toxin

d) Toxoid

Option a – Vaccine

Yeasts come under a group of.

a) Bacteria

b) Fungi

c) Protozoa

d) Virus

Option b – Fungi

Sterols belong to the class of.

a) Lipids

b) Waxes

c) Carbohydrates

d) Proteins

Option a – Lipids

A hypotonic solution can be made isotonic by the addition of.

a) Sodium chloride

b) Potassium chloride

c) Calcium chloride

d) Magnesium chloride

Option a – Sodium chloride

Tuberculosis is diagnosed by.

a) Widal test

b) Elisa’s test

c) Mantoux test

d) Alerts method

Option c – Mantoux test

The rod-shaped bacteria are.

a) Coccus

b) Spirilla

c) Bacillus

d) Vibrious

Option c – Bacillus

Widal test is used for the diagnosis of.

a) Typhoid

b) AIDS

c) Jaundice

d) Meningitis

Option a – Typhoid

The disease is caused by Entamoeba histolytica.

a) Malaria

b) Trypanosomiasis

c) Filariaisis

d) Amoebiasis

Option d – Amoebiasis

The presence of pathogenic bacteria in his blood is called.

a) Toemia

b) Septicemia

c) Bacteremia

d) Anemia

Option b – Septicemia

Dettol is used as.

a) Antiseptic

b) Disinfectant

c) Antimicrobial

d) Anemia

Option a – Antiseptic

The diameter of the mesh aperture in the IP disintegration test apparatus is given below.

a) 2.00mm

b) 4.00mm

c) 3.00mm

d) 1.50mm

Option a – 2.00mm

One of the following mills works on both the principles of attrition and impact.

a) Cutter mill

b) Hammer mill

c) Roller mill

d) Fluid energy mill

Option d – Fluid energy mill

Choose the correct excipients for enhancing solubility in tablet manufacture.

a) PEG

b) Microcrystalline cellulose

c) Talc

d) Lactose

Option a – PEG

The area under the serum concentration-time curve of a drug represents.

a) The biological half-life of the drug

b) The amount of drug in the original dosage from

c) The amount of drug absorbed

d) The amount of drug excreted in the uring

Option c – The amount of drug absorbed

The ‘Unna parte’ contains.

a) Zinc oxide

b) Zinc oxide and Sulphur

c) Zinc oxide and Gelatin

d) zinc oxide and Boric acid

Option d – zinc oxide and Boric acid

“Capping” in tablets occurs due to.

a) Entrapment of Air

b) Excessive moisture

c) Increased rate of evaporation

d) None of above

Option a – Entrapment of Air

The dip tube in an aerosol container is made from which one of the following?

a) Polypropylene

b) Glass

c) Stainless steel

d) Aluminium

Option a – Polypropylene

Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilization.

a) NADPH+H+

b) FAD

c) NAD

d) NADH+H+

Option d – NADH+H+

The international unit of Vitamin A is equivalent to the activity caused by.

a) 0.3 µg of Vitamin A alcohol.

b) 0.344 µg of Vitamin A alcohol

c) 0.6 µg of Vitamin A alcohol

d) ug of Vitamin A alcohol

Option d – ug of Vitamin A alcohol

Compounds having the same structural formula about differing in the spatial configuration are known as.

a) Epimers

b) Anomers

c) Optical isomers

d) Stereoisomers

Option d – Stereoisomers

Retinol is transported in the blood bound to.

a) Aporetinol binding protein

b) 2-Globulin

c)-Globulin

d) Albumin

Option a – Aporetinol binding protein

Among the following preparation, which one will be the most irritating to the eye?

a) Purified water

b) 0.7% NaCl solution

c) 0.9% NaCl sol.

d) 1% NaCl solution

Option a – Purified water

Carotene precursor of Vitamin A is oxidatively cleaved by.

a) Carotene dioxygenase

b) Oxygenase

c) Hydroxylase

d) Transferase

Option a – Carotene dioxygenase

Fat-soluble vitamins are.

a) Soluble in alcohol

b) One or more propane units

c) Stored in liver

d) All of these

Option d – All of these

Preformed Vitamin A is supplied by.

a) Milk, Fat, and Liver

b) All yellow vegetables

c) All yellow fruits

d) Leafy green vegetables

Option a – Milk, Fat, and Liver

Retinol and Retinal are interconverted requiring dehydrogenase or reductase in the presence of.

a) NAD or NADP

b) NADPH

c) FAD

d) NADH+H+

Option d – NADH+H+

VRDL antigen is to be tested and analyzed by the.

a) Drug inspector

b) Excise commissioner

c) Serologist and chemical examiner

d) Drug controller of India

Option d – Drug controller of India

Chloramphenicol comes under schedule.

a) G

b) H

c) W

d) P

Option b – H

The aldose sugar is.

a) Glycerose

b) Ribulose

c) Erythrulose

d) Dihydroxyacetone

Option a – Glycerose

A triose sugar is.

a) Glycerose

b) Ribulose

c) Erythrulose

d) Fructose

Option a – Glycerose

A pentose sugar is.

a) Dihydroxyacetone

b) Ribulose

c) Erythrulose

d) Glucose

Option b – Ribulose

Schedule D as per D and CAct is concerned with.

a) List of drugs exempted from the provision of import of drugs

b) Diseases or aliments which a drug may not purport to prevent or cure

c) Requirement of factory premises

d) List of prescription drugs

Option a – List of drugs exempted from the provision of import of drugs

One of the following Ex-Officio members of the state pharmacy council.

a) Chief pharmacist of a government hospital

b) Chief administrative medical officer of the state

c) Registered pharmacist

d) Assistant drug controller

Option b – Chief administrative medical officer of the state

The education regulation is published in the official gazette.

a) Ministry of Education

b) Central government

c) Drug Controller

d) President, Pharmacy Council of India

Option b – Central government

The total area required for the manufacture of cosmetics aerosol as per the Schedule M of the Drug and Cosmetics Act is.

a) 15 m²

b) 25 m²

c) 30 m²

d) 35 m²

Option c – 30 m²

State pharmacy council should have the following number of elected members.

a) Six

b) Nine

c) Five

d) Seven

Option a – Six

The Schedule Drugs and cosmetics act deals with the requirement and guidelines of clinical trials, import, and manufacture of new drugs.

a) Schedule – O

b) Schedule – M

c) Schedule – F

d) Schedule – Y

Option d – Schedule – Y

Which test organism is used for the microbiological assay of ampicillin?

a) Micrococcus luteus

b) Staphylococcus aureus

c) Bacillus subtillis

d) E. Coli

Option c – Bacillus subtillis

Staphylococcus aureus produces a pigment during its growth.

a) Red color

b) Green color

c) Yellow color

d) Black color

Option a – Red color

The particle size of the dispersed solid in a suspension is usually greater than.

a) 0.5 µm

b) 0.4 μm

c) 0.2 μm

d) 0.1 μm

Option a – 0.5 µm

A retardant material that forms a hydrophilic matrix in the formulation of matrix tablets is.

a) H.P.M.C.

b) C.A.P

c) Polyethylene

d) Carnauba wax

Option a – H.P.M.C.

Measurement of particle size in pharmaceutical aerosols is by. p) Cascade Impactor q) Light Scatter Decay r) Karl Fichser Method s) IR spectroscopy

a) (p), (q)

b) (q), (r)

c) (r). (s)

d) (p), (s)

Option a – (p), (q)

How many parts of 10% ointment be mixed with 2 parts of 15% ointment to get 12% ointment?

a) 2

b) 3

c) 5

d) 6

Option b – 3

Which one of the following drugs is metabolized to a cytotoxic product?

a) Vincristine

b) Dactinomycin

c) 5Fluoroucil

d) Lomustine

Option c – 5Fluoroucil

Which one of the following agents shows cytotoxicity that is cell-specific?

a) Methotrexate

b) Dactinomycin

c) Cisplastin

d) Mechlorethamine

Option a – Methotrexate

Which one of the following antiviral agents exhibits the greatest selective toxicity for the invading virus?

a) Interferon

b) Amantadine

c) Acyclovir

d) Zidovudine

Option c – Acyclovir

In which one of the following conditions would aspirin be contraindicated?

a) Myalgia

b) Fever

c) Peptic ulcer

d) Rheumatoid

Option c – Peptic ulcer

A water-soluble substance is used as a coating material in the microencapsulation process.

a) Polyethylene

b) Silicone

c) Hydroxyethylcellulose

d) Paraffin

Option c – Hydroxyethylcellulose

Killer-Kilani Test is an identification test used for

a) Digitalis

b) Clove

c) Fennel

d) Senna

Option a – Digitalis

Who is regarded as the father of medicine?

a) Paracelsus

b) Aristotle

c) Galen

d) Hippocrates

Option d – Hippocrates

Ruthenium red is used to detect.

a) Gum

b) Lipids

c) Wax

d) Mucilage

Option a – Gum

Isapgol seeds are used.

a) Laxative

b) Purgative

c) Cathartic

d) Digestive

Option a – Laxative

Dried latex of the drug is used except….

a) Opium

b) Gutta-percha

c) Papain

d) Balsam

Option d – Balsam

Soxhlet apparatus is used for

a) Filtration

b) Clarification

c) Extraction

d) Size Reduction

Option c – Extraction

Digitalis is mainly used.

a) Cardiotonic

b) Analgesic

c) CNS stimulant

d) Purgative

Option a – Cardiotonic

Coriander contains chiefly ……

a) L-borneol

b) Pinene

c) D-linalool

d) Gernniail

Option c – D-linalool

Borntrager’s test is used to identify……

a) Cumarins

b) Saponins

c) Anthroquinones

d) Steroids

Option c – Anthroquinones

Vinca belongs to the category of crude drug …

a) Antitumor

b) Anti-Tussive

c) Diuretics

d) Anti-Malaria

Option a – Antitumor

Topically applied silicone oils are …….

a) Natural oils

b) Semi-synthetic oil

c) Polymers

d) Shark liver oil

Option c – Polymers

A glycoalkaloid….

a) Contains sulphur in addition to nitrogen in its molecule.

b) Is glycosidic in nature

c) Can be hydrolyzed to an alkaloid

d) Always contain endocyclic sulphur in its molecule

Option b – Is glycosidic in nature

Which of the following statement is true for the ginseng root?

a) It is among the most traded plant in Brazil

b) It is obtained from Panax ginseng and Panax quinquefolium.

c) It is obtained from young plants of six months to one year of age.

d) It contains derivatives of quinindiol

Option b – It is obtained from Panax ginseng and Panax quinquefolium

The drug hashish is produced from the flowers of the tree of…….

a) Neem

b) Hemp

c) Rose

d) Tulsi

Option b – Hemp

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