Molecular Basis of Inheritance Class 12 MCQ. We covered all the Molecular Basis of Inheritance Class 12 MCQ in this post for free so that you can practice well for the exam.
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MCQ on Molecular Basis of Inheritance for Students
Which of the following gene of the lac operon codes for ß-galactosidase?
(A) z gene
(B) a gene
(C) i gene
(D) y gene
Option a – z gene
Which of the following enzyme catalyzes the transcription of all types of RNA in bacteria?
(A) DNA-dependent DNA polymerase
(B) RNA-dependent DNA polymerase
(C) DNA-dependent RNA polymerase
(D) RNA-dependent RNA polymerase
Option c – DNA-dependent RNA polymerase
Which of the following statement is INCORRECT with respect to repetitive DNA sequences?
(A) They show a high degree of polymorphism.
(B) They are an integral part of paternity testing in case of disputes.
(C) They have a direct protein-coding function.
(D) They form the basis of DNA fingerprinting.
Option c – They have a direct protein-coding function.
Which of the following is an application of DNA fingerprinting analysis?
(A) Tool in forensic investigations
(B) Determination of population diversity
(C) Determination of genetic diversities within a population
(D) All of the above
Option d – All of the above
The process of DNA replication is termed as
(A) conservative
(B) continuous
(C) semi-conservative
(D) complementary
Option c – semi-conservative
Which of the following enzymes inhibits the process of transformation?
(A) Protease
(B) DNase
(C) RNase
(D) All of the above
Option b – DNase
……… binds to the stop codon and terminates the process of translation.
(A) Initiation factor
(B) Sigma factor
(C) Methyl guanosine triphosphate
(D) Release Factor
Option d – Release Factor
Which of the following confers stability to the helical structure of DNA?
(A) Base pair stacking
(B) H-bonds
(C) 2′-OH group
(D) Both (A) and (B)
Option d – Both (A) and (B)
Which of the following is a ribozyme?
(A) 5srRNA
(B) snRNA
(C) 23S rRNA
(D) hnRNA
Option c – 23S rRNA
DNA extraction from a culture of E. coli cells after transfer from 15N to 14N medium would form a single hybrid band on density gradient centrifugation during which generation?
(A) I Generation
(B) II Generation
(C) III Generation
(D) IV Generation
Option a – I Generation
The untranslated region(s) is/are present
(A) in between the coding sequence of the mRNA.
(B) before the stop codon and after the start codon.
(C) only at the 5′ end of the mRNA.
(D) at both the 3′ and 5′ end of the mRNA.
Option d – at both the 3′ and 5′ end of the mRNA.
Identify which of the following is INCORRECT with respect to the Hershey-Chase experiment.
(A) Viruses were grown on a medium containing radioactive sulfur or phosphorous.
(B) Radioactive phages were allowed to infect E. coli bacteria.
(C) The viral coats were removed from the bacteria by enzymatic action.
(D) The level of radioactive 35S was detected in the supernatant, after centrifugation.
Option c – The viral coats were removed from the bacteria by enzymatic action.
Which of the following statement is TRUE with respect to DNA?
(A) It directly codes for the synthesis of proteins.
(B) It is more labile and reactive than RNA.
(C) It is preferred for the storage of genetic information.
(D) It contains the 2′-OH group.
Option c – It is preferred for the storage of genetic information.
DNA-dependent DNA polymerase catalyzes polymerization in a discontinuous manner on the template with polarity
(A) 5′-3′
(B) 3′-5′
(C) 2′-5′
(D) either 5′-3 or 3′-5′
Option a – 5′-3′
Assertion: Viruses mutate and evolve faster than DNA. Reason: Viruses have an RNA genome.
(A) Both assertion and reason are true and the reason is the correct explanation of assertion.
(B) Both assertion and reason are true but the reason is not the correct explanation of assertion.
(C) Assertion is true but the reason is false.
(D) Both assertion and reason are false.
Option a – Both assertion and reason are true and the reason is the correct explanation of assertion.
If 5′- AUGCCAUGCUG – 3′ is an mRNA transcript, identify which of the following sequences correctly represents the coding strand.
(A) 5′-TACGGTACGAC-3′
(B) 5′-ATGCCATGCTG-3′
(C) 3′-ATGCCATGCTG-5′
(D) 3′-CAGCATGGCAT-5′
Option b – 5′-ATGCCATGCTG-3′
RNA polymerase is capable of catalyzing which of the following step(s) of transcription independently?
(A) Initiation
(B) Elongation
(C) Termination
(D) All of the above
Option b – Elongation
Which of the following is INCORRECT with respect to mutations of the genetic code?
(A) The insertion of one base is termed a frameshift mutation.
(B) Deletion of a sequence of fourteen bases results in a shift of the reading frame from the point of deletion.
(C) Insertion of seven bases shifts to the reading frame, that point onwards.
(D) The deletion of five codons alters the reading frame.
Option d – The deletion of five codons alters the reading frame.
Read the following statements and choose the correct option. Statement I: Thread-like bodies present in the nucleus that can be stained are called chromatin. Statement II: Euchromatin is the transcriptionally inactive chromatin present in the nucleus.
(A) Statement I is correct and statement II is incorrect.
(B) Statement II is correct and statement I is incorrect.
(C) Both statement I and statement II are correct.
(D) Both statement I and statement II are incorrect.
Option a – Statement I is correct and statement II is incorrect.
We covered all the molecular basis of inheritance class 12 MCQ above in this post for free so that you can practice well for the exam.
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